Oxalobacter formigenes: a potential tool for the treatment of primary hyperoxaluria type 1
نویسندگان
چکیده
منابع مشابه
Re: Oxalobacter formigenes: Opening the Door to Probiotic Therapy for the Treatment of Hyperoxaluria.
OBJECTIVE The aim of this study was to determine the early effect of the administration of Oxalobacter formigenes on the metabolic pattern of patients with calcium oxalate stones, comparing it with potassium magnesium citrate (KMgCit). MATERIALS AND METHODS Eighty patients were randomized to receive either 30 mEq of KMgCit or 700 million O. formigenes, both twice a day. Serum creatinine, seru...
متن کاملEfficacy and safety of Oxalobacter formigenes to reduce urinary oxalate in primary hyperoxaluria.
BACKGROUND Primary hyperoxaluria (PH) is a rare genetic disease, in which high urinary oxalate (Uox) cause recurrent kidney stones and/or progressive nephrocalcinosis, often followed by early end-stage renal disease, as well as extremely high plasma oxalate, systemic oxalosis and premature death. Oxalobacter formigenes, an anaerobic oxalate degrading bacterium, naturally colonizes the colon of ...
متن کاملAnabolic Incorporation of Oxalate by Oxalobacter formigenes.
Cell-free lysates of the strict anaerobe Oxalobacter formigenes contained the following enzymatic activities: oxalyl coenzyme A reductase, glyoxylate carboligase, tartronic semialdehyde reductase, and glycerate kinase. NAD(P)-linked formate dehydrogenase, serine-glyoxylate aminotransferase, and NAD(P) transhydrogenase activities were not detected. These results support the hypothesis that O. fo...
متن کاملcomparison of zoe and vitapex for canal treatment of necrotic primary teeth
چکیده ندارد.
15 صفحه اولGenome Sequence of Oxalobacter formigenes Strain HC-1
The lack of Oxalobacter formigenes colonization of the human gut has been correlated with the formation of calcium oxalate kidney stones and also with the number of recurrent kidney stone episodes. Here, we present the genome sequence of HC-1, a human strain isolated from an individual residing in Iowa, USA.
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ژورنال
عنوان ژورنال: Kidney International
سال: 2006
ISSN: 0085-2538
DOI: 10.1038/sj.ki.5001707